Randy S. D’Amico, MD is a board-certified neurosurgeon in New York City specializing in the surgical treatment of brain tumors and spine tumors. He is the Director of the Brain and Spine Metastasis Program at Lenox Hill Hospital, part of Northwell Health, and is recognized nationally for combining advanced brain tumor surgery techniques with connectomics, spatial computing, and AI-guided surgical planning to deliver precise, personalized care.

Dr. D’Amico - a premiere neurosurgical oncologist - treats the full spectrum of primary brain tumors — including glioblastoma, astrocytoma, oligodendroglioma, and meningioma — as well as metastatic brain tumors from cancers such as lung cancer, breast cancer, and melanoma. His surgical approach focuses on maximal safe resection while preserving the brain’s critical language networks, motor networks, and cognitive networks, an approach known as onco-functional balance.

As a leading brain tumor surgeon and clinical researcher, Dr. D’Amico leads studies exploring how tumors and their treatments affect the brain’s functional connectivity. His work has been published in leading neurosurgery and neuro-oncology journals, and he regularly lectures at national and international neurosurgical conferences.

Patients and referring physicians choose Dr. D’Amico for his ability to combine innovative surgical technology with compassionate, patient-centered care. He collaborates closely with a multidisciplinary brain tumor team to develop individualized treatment plans, and is committed to educating patients, families, and the public about the latest advances in brain tumor surgery, connectomics, and cancer care.

Patients often seek a second opinion to confirm treatment options, review imaging, and understand whether advanced techniques such as connectomics-guided resection or minimally invasive approaches are appropriate. Dr. D’Amico offers rapid, thorough second opinions for newly diagnosed, complex, and recurrent brain tumors.

Why Patients Choose Dr. D’Amico

• Network-Preserving Neurosurgery using connectomics

• Advanced Tumor Resection for metastatic, recurrent, or difficult lesions

• Awake Brain Mapping for speech and motor preservation

• Minimally Invasive Approaches when appropriate

• Multidisciplinary Expertise with oncology, radiation, and neuroscience teams

• Expedited Second Opinions for urgent cases

Dr. D’Amico provides neurosurgical care throughout:

• Manhattan (Upper East Side, Upper West Side, Midtown)

• Brooklyn

• Queens

• The Bronx

• Long Island

• Bergen County, NJ

• Westchester County

He performs surgery at Lenox Hill Hospital on the Upper East Side of Manhattan (100 E 77th St, New York, NY 10075), offering convenient access for patients across the tri-state region.